Lizzy Caplan – Janice Ian
Lizzy Caplan played the absolutely unforgettable Janice Ian in 2004’s Mean Girls, starring alongside Lindsay Lohan and Rachel McAdams. She is completely unrecognizable in real life, as she sports a more mainstream haircut and makeup style in her everyday life.
Lena Heady – Cersei Lannister
Lena Heady gives an absolutely brilliant performance as Cersei Lannister in the much beloved HBO series Game of Thrones. However, Heady could not look more different from her character in real life. For one, she is covered in tattoos.